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Once you’ve activated the preinstalled WordPress Backup plugin, go to Manage/Backup to access your backup options. You have a choice of saving it to the server, downloading a copy or emailing yourself a copy. I would choose to download a copy or email it because saving it to your server won’t help you if your server fails.

Note that this method doesn’t backup your themes, plugins or any modifications that you may have done to them. When you do any major design or plugin changes, you should also make a copy of your themes and plugin folders (you can find them in the wp-content folder)… use an FTP program like FireFTP or your host’s web based file manager to do this.